TP53 p.S215I Reference Standard
CBP10206
詢(xún) 價(jià)
索取COA
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫(kù)
| Introduction | |
| Format | Genomic DNA |
| Description | TP53 S215I lies within the DNA-binding domain of the Tp53 protein (PMID: 15510160). S215I is predicted to confer a loss of function to the Tp53 protein, as demonstrated by the inability to transactivate Mdm2 in-vitro (PMID: 17325666). |
| Technical Data | |
| DNA Change | c.644G>T |
| AA Change | p.S215I |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | ENST00000269305 |
| Cosmic ID | COSM11450 |
| Chr position(GRCh37) | chr17:7578205 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 2-8℃ |
| Expiry | 36 months from the date of manufacture |
