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首頁(yè) /藥靶模型 /GPCR靶點(diǎn)細(xì)胞 /Class A(Rhodopsin) /CRTH2(DP2)/CHO

CRTH2(DP2)/CHO

CBP71380

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I. Background
CRTH-2 is a 7-transmembrane G-protein coupled receptor that is expressed by activated Th2 cells and eosinophils.
 
II. Introduction
Host Cell:

CHO

Stability: 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium: 90% FBS+10% DMSO
Culture Medium: F12K+10%FBS+5ug/ml puromycin
Mycoplasma Status: Negative
Storage: Liquid nitrogen immediately upon delivery
Application(s):

Functional assays for CRTH2

Transducer: Gi
 
Ⅲ. Description of Host Cell Line
Organism: Hamster
Tissue: Ovary
Morphology: Epithelial
Growth Properties: Adherent
 
Ⅳ. Representative Data

Figure 1. Recombinant CRTH2(DP2)/CHO constitutively expressing CRTH2(DP2).

Figure 2. HTRF CAMP Assay with CRTH2(DP2) CHO Cells (C1).


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