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首頁(yè) /藥靶模型 /GPCR靶點(diǎn)細(xì)胞 /Class A(Rhodopsin) /CXCR3/CHO

CXCR3/CHO

CBP71371

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I. Background
CXCR3 (C-X-C Motif Chemokine Receptor 3) is a Protein Coding gene. Diseases associated with CXCR3 include Cutaneous Lupus Erythematosus and Pulmonary Sarcoidosis. Among its related pathways are CCR5 Pathway in Macrophages and Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and chemokine receptor activity. 
 
II. Introduction
Host Cell:

CHO

Stability: 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium: 90% FBS+10% DMSO
Culture Medium: N/A
Mycoplasma Status: Negative
Storage: Liquid nitrogen immediately upon delivery
Application(s):

Functional assay for CXCR3

Transducer: Gi
 
Ⅲ. Description of Host Cell Line
Organism: Hamster
Tissue: Ovary
Morphology: Epithelial
Growth Properties: Adherent
 
Ⅳ. Representative Data

Figure 1. RD CXCL11 efffect on CHO-CXCR3 clone 11.


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