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首頁(yè) /藥靶模型 /GPCR靶點(diǎn)細胞 /Class A(Rhodopsin) /CXCR6/CHO

CXCR6/CHO

CBP71365

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I. Background
CXCR6 (C-X-C Motif Chemokine Receptor 6) is a Protein Coding gene. Diseases associated with CXCR6 include Type 1 Diabetes Mellitus 22 and Immune Deficiency Disease. Among its related pathways are Akt Signaling and GPCR downstream signalling. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and C-X-C chemokine receptor activity. An important paralog of this gene is CCR6.
 
II. Introduction
Host Cell:

CHO

Stability: 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium: 90% FBS+10% DMSO
Culture Medium: N/A
Mycoplasma Status: Negative
Storage: Liquid nitrogen immediately upon delivery
Application(s):

Functional assay for CXCR6

Transducer: Gi
 
Ⅲ. Description of Host Cell Line
Organism: Hamster
Tissue: Ovary
Morphology: Epithelial
Growth Properties: Adherent
 
Ⅳ. Representative Data

Figure 1. CXCL16 effect on CHO-CXCR6 clone 2.

 

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